The Quantitative Structure-Activity Relationships of Antifungal Active 2- (p-Substituted-Phenyl) Benzoxazole Derivatives Against Candida Albicans Using The Combinations of Some Hydrophobic, Electronic
نویسندگان
چکیده
منابع مشابه
In vitro activity of antifungal combinations against Candida albicans biofilms.
OBJECTIVES The aim of the present study was to evaluate the in vitro activity and synergism of the combinations of amphotericin B/caspofungin and amphotericin B/posaconazole against Candida albicans, grown either as planktonic cells or in biofilms. METHODS Ten C. albicans bloodstream isolates used in this study were collected from intensive care patients admitted to the Vienna University Hosp...
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In this study, antifungal property of olive leaf extracts against Candida albicans PTCC-5027 was examined. Fresh olive leaf extracts were prepared using distilled water in a Soxhlet apparatus. The antifungal activity of the extract was analyzed by measuring the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC), using the microdilution test and disc diffusion assa...
متن کاملAntifungal synergy of theaflavin and epicatechin combinations against Candida albicans.
New antifungal agents are required to compensate for the increase in resistance to standard antifungal agents of Candida albicans, which is an important opportunistic fungal pathogen that causes minor infections in many individuals but very serious infections in those who are immune-compromised. In this study, combinations of theaflavin and epicatechin are investigated as potential antifungal a...
متن کاملStructure–Activity Relationships among Antifungal Nylon-3 Polymers: Identification of Materials Active against Drug-Resistant Strains of Candida albicans
Fungal infections are a major challenge to human health that is heightened by pathogen resistance to current therapeutic agents. Previously, we were inspired by host-defense peptides to develop nylon-3 polymers (poly-β-peptides) that are toxic toward the fungal pathogen Candida albicans but exert little effect on mammalian cells. Based on subsequent analysis of structure-activity relationships ...
متن کاملAntifungal combinations against Candida albicans biofilms in vitro.
Candida biofilms display increased resistance to most antifungal agents. We have evaluated the efficacy of combinations of fluconazole (FLC), amphotericin B, and caspofungin (CSP) against Candida albicans biofilms in vitro. Indifference was observed for all the combinations of paired antifungal agents when a checkerboard titration method was used. Time-kill experiments revealed an antagonistic ...
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ژورنال
عنوان ژورنال: Ankara Universitesi Eczacilik Fakultesi Dergisi
سال: 1987
ISSN: 1015-3918
DOI: 10.1501/eczfak_0000000483